roche santaris pharma

| August 2, 2022 We are a force of over 90,000 people working together across more than 100 countries. The agreement also includes milestone payments of up to $1 billion.. Roche, based in Basel, Switzerland, said in a statement that it would make an initial cash payment of $250 million for privately held Santaris, which specializes in relatively new RNA-targeting. The Swiss company, which exited the RNAi field in 2010 as part of an R&D restructure, believes Santaris' RNA-targeting technology could underpin the discovery and development of a new class of medicines. The RICC team comprises research specialists in oligonucleotide and conjugate chemistry, molecular biology, cell biology, pharmacokinetics, and bioinformatics. [25], Isis Pharmaceuticals filed a patent infringement lawsuit against Santaris Pharma A/S in the United States District Court of the Southern District of California in September 2011. Previously, Roche was involved in RNA-targeting therapeutic research, but decided to walk away from this research area in 2010. In a bid to expand the discovery and development of RNA-targeting medicines, Roche announced that it has entered into an agreement to acquire Denmark-based privately-held biopharmaceutical company Santaris Pharma. Customer Service. LNA is a modification of RNA, containing an oxymethylene bridge between the 2 oxygen and 4 carbon in the ribose ring. This has the potential to be used as treatment for patients with hyperlipidemia. The Swiss company, which exited the RNAi field in 2010 as part of an R&D restructure, believes Santaris' RNA-targeting technology could underpin the discovery and development of a new class of medicines. Genentech Pipeline. Roche will make additional payments of as much as $200 million if the company reaches certain milestones. About Roche Headquartered in Basel, Switzerland, Roche is a leader in research-focused healthcare with combined strengths in pharmaceuticals and diagnostics. Roche Diabetes Care er en af de strste leverandrer af blodsukkermleudstyr til diabeteskontrol. Roche plans to maintain Santaris Pharma's operations in Denmark, where the existing site will be renamed Roche Innovation Center Copenhagen. Roche has announced its agreement to acquire Santaris Pharma, a privately held biopharmaceutical company based near Copenhagen, Denmark. Santaris Pharma A/S was a biopharmaceutical company founded in 2003 in Copenhagen, Denmark. Create a company page Copenhagen Area, Denmark Group Leader, Bioinformatics Santaris Pharma . Haz clic en Gestionar ajustes para obtener ms informacin y gestionar tus opciones. 2008: Biotech grant from Danish Advanced Technology for microRNA antagonist research for 45m DKK. The acquisition is expected to close later in the. Roche has brought many highly effective drugs onto the market and is a world leader in innovative cancer drugs. [6], Santaris developed LNA-based drugs to identify and design drug candidates. Please be aware that we do not take any responsibility for accessing such information which may not comply with any legal process, regulation, registration or usage in the country of your origin. Worlds first microRNA-medicine feb. 2007 - okt. $ + tax Roche will be responsible for the subsequent development and commercialization of products arising from the alliance. Phone: +46 8 588 941 50, Risk genes for idiopathic pulmonary fibrosis revealed, New multiomics study of nonalcoholic fatty liver disease, Gesynta Pharma prepares Phase II study of GS-248 in endometriosis, Curida acquires biologics manufacturer Diatec, Aqilion acquires anti-inflammatory program from LEO Pharma, LEO Pharma sells portfolio of four products to Cheplapharm. Roche plans to maintain Santaris Pharma's operations in Denmark, where the existing site will be renamed Roche Innovation Center Copenhagen. Hoffmann-La Roche: ClinicalTrials.gov Identifier: NCT02508090 Obsolete Identifiers: NCT02031133: Other Study ID Numbers: NP29711 : First Posted: July 24, 2015 Key Record Dates: Last Update . Aug. 5, 2014. Today there are many disease targets that are very challenging or even impossible to reach with small molecules or antibodies. On Friday, October 7, 2011, all the allegations initiated by Exiqon against Santaris were dismissed by the arbitration court. Swiss pharmaceutical manufacturer Roche has agreed to acquire Santaris Pharma, a privately owned biopharmaceutical company based near Copenhagen, Denmark. At the same time, this novel class of drugs offers the means to address disease targets that have previously been undruggable with conventional drug therapies such as small molecules or antibodies. Roche has been active in the space as well, acquiring Santaris Pharma and its Locked Nucleic Acid platform in 2014 for $250 million upfront, and then in November licensing Ionis Pharmaceuticals' antisense drug for Huntington's disease. Home Buyers Are Moving Farther Away Than Ever Before, You Can Thank the Fed for Boosting the $1.5 Billion Powerball Jackpot, Opinion: What to Expect in the 2022 Midterms, Opinion: The Pacifics Missing F-15 Fighters, Opinion: Jerome Powells Not for TurningYet, Opinion: Trump Casts a Shadow Over Arizonas GOP, Opinion: Putins Nonnuclear War in Ukraine, Putinisms: Vladimir Putins Top Six One Liners, Ukrainians Sift Through Debris; Civilians Urged to Leave Eastern Regions, Opinion Journal: The Trump-Modi Friendship, Russian Oil Is Fueling American Cars Via Sanctions Loophole. [7] Santaris designed LNA oligonucleotides as antisense therapeutics to complement specific mRNA and microRNA sequences. Santaris' locked nucleic acid (LNA) platform can potentially facilitate development of RNA-targeting therapies -- an area that has a lot of promise, but has been very challenging for researchers. Puedes cambiar tus opciones en cualquier momento desde tus controles de privacidad. Our R&D activities are focused on applying excellent science to discover and develop potential new medicines with the goal of becoming first-in-class or best-in-class therapeutics. Roches Innovation Center in Copenhagen is a leader in the field of Nucleic Acid-Based Medicines focusing on Ribonucleic acid (RNA) targeting drugs. No Comments. "Roche and Santaris Pharma have complementary capabilities that will help us realise breakthrough medicines," stated Mr J Donald deBethizy, president and CEO of Santaris Pharma. SPC-4955 is a novel treatment for cholesterol. The PCSK9 program also has the potential to treat patients with hyperlipidemia. Under the terms of the agreement, Roche will make an upfront cash payment of USD 250 million to Santaris Pharma shareholders and make additional contingent payments of up to The loan facility provides Bavarian, Bristol-Myers Squibb has acquired all of the outstanding capital stock of Cormorant, a private, Stockholm, Sweden-based pharmaceutical company focused on the development of therapies for cancer and rare diseases. 2011: Finalist for 2011 Scrip Awards in the "Clinical Research Team of the Year" category. Roche also announced that the acquisition would give it access to a series of drugs for diseases that have proved hard to treat. BASEL, SwitzerlandRoche has announced that it will be acquiring privately held Santaris Pharma, a biopharmaceutical company based near Copenhagen, Denmark, that specializes in the development of next-generation antisense products.Per the terms of the agreement, Roche will pay Santaris Pharma shareholders $250 million up front, with the potential for additional contingent payments of up to . [10] It inhibits the protein which controls the number of receptors responsible for removing LDL cholesterol particles from the blood. Roche is to buy the private Danish firm Santaris Pharma, whose technology to discover drugs targeting RNA is designed to overcome the limitations of previous antisense and small interfering RNA (siRNA) technologies. NEW YORK (GenomeWeb) Isis Pharmaceuticals and Santaris Pharma are currently negotiating a settlement to their roughly three-year-old patent-infringement lawsuit and believe there is "strong potential to settle" the litigation instead of going to trial, according to court documents filed this month. You may change your billing preferences at any time in the Customer Center or call As part of the deal, Roche will make an upfront cash payment of $250m to Santaris shareholders and make additional contingent payments of up to $200m based on Pharmaceutical Business review is using cookies Under the terms of the agreement, Roche will make an upfront cash payment of USD 250 million to Santaris Pharma shareholders and make additional contingent payments of up to USD 200 million based on the . We believe the LNA platform provides the means to efficiently discover and develop an important new class of medicines that may address the significant needs of patients across multiple therapeutic areas,said John C. Reed, Head of Roche Pharma Research and Early Development. In August 2014, Santaris was acquired by Roche for $450 million. PDF. 2006: Partnership with Enzon for cancer therapeutics. 2003: Santaris founded through a merger of Cureon and Pantheco. Under the terms of the agreement, Roche will make an upfront cash payment of USD 250 million to Santaris Pharma shareholders and make additional contingent payments of up to . Located in Hrsholm, near Copenhagen, Roche Innovation Center Copenhagen (RICC) employs approximately 70 employees. 17.30 ikke lngere er ansat hos Santaris Pharma, men derimod hos Roche Innovation Center Copenhagen. Sign In. Biopharmaceutical company Santaris Pharma will be acquired by Roche for a total consideration of up to $450 million, comprised of an upfront cash payment of $250 million and additional contingent payments of up to $200 million based on the achievement of certain predetermined milestones. [16] We are delighted that you'd like to resume your subscription. Founded in 2003, Santaris Pharma is headquartered in Denmark. EZN-3042 is also an inhibitor, which acts against Survivin. Image: John C. Reed, Head of Roche Pharma Research and Early Development, Aqilionhas strengthened its pipeline with an innovative development program in the field of chronic inflammation. [1] The company also had a branch in San Diego, California that opened in 2009. Roche's European-based R&D arm pRED has closed a deal to buy Denmark's Santaris Pharma, paying $250 million upfront with another $200 million up for grabs in potential milestones if the research . For other uses, see Roche (disambiguation).. Coordinates: 473331N 73622E / 47.558624N 7.606018E / Pharma Consulting & Analytics; Data Feeds and APIs; Evaluate Vantage. According to a press release from Roche, the acquisition, which is subject to customary closing conditions, is expected to close in August 2014. Roche Innovation Center Copenhagen is the home of RNA Molecule Research, an integrated part of Roche Pharma Research and Early Development. The acquisition gives Bristol-Myers Squibb full rights to Cormorants HuMax-IL8 antibody program and the lead candidate HuMax-IL8, a Phase 1/2 monoclonal, LEO Pharma has announced the sale of a portfolio of four non-core products to Cheplapharm for EUR 300 million. Customer Service. . On August 6, 2014, Roche Holding AG acquired life science company Santaris Pharma A/S from Gilde Healthcare for 250M USD Acquisition Highlights. Roche plans to maintain Santaris Pharma's operations in Denmark, where the existing site will be renamed Roche Innovation Center Copenhagen. The deal is structured with an upfront cash payment of $250 million and additional . Under the terms of the agreement, Roche will make an upfront cash payment of USD 250 million to Santaris Pharma shareholders and make additional contingent payments of up to . Roche Pharmaceuticals er den strste leverandr af lgemidler til danske hospitaler. Santaris Pharma A/S (Hoersholm, Denmark) was a platform company stabilizing oligonucleotides using their LNA technology to enable the oligonucleotide's use in therapeutic products. R&D Laboratory Technician Novo Nordisk A/S jul. Santaris Pharma's key technology is its proprietary Locked Nucleic Acid (LNA) platform that has contributed Roche, based in Basel, Switzerland, said in a statement that it would make an initial cash payment of $250 million for privately held Santaris, which specializes in relatively new RNA-targeting therapeutics. Read more: LEO Pharmas, NLS Media Group AB Postal address: Kindstugatan 1, 111 31 Stockholm. Roche has agreed to acquire Santaris Pharma, a privately held biopharmaceutical company based near Copenhagen, Denmark. Roche will make an upfront cash payment of $250 million to shareholders of Santaris Pharma along with milestone payments of $200 million. Last month, U.S.-based Seragon Pharmaceuticals Inc. was bought by Roche for $1.725 . [3] With its LNA technology, Santaris developed drugs for a range of diseases using microRNA and mRNA. You will be charged Santaris Pharma A/S had two novel drug candidates for the treatment of solid tumors and lymphomas, EZN-2968 and EZN-3042. Hagedorn Research Institut - Gentofte R&D Laboratory Technician Santaris Pharma A/S aug. 2011 - . NEW YORK (GenomeWeb) - Roughly four months after Roche acquired Santaris Pharma, the locked nucleic acid drugmaker now known as Roche Innovation Center Copenhagen (RICC) has transitioned into the centerpiece of the Roche's return to RNA therapeutics. Create a new article. 2012 - dec. 2013 1 r 6 mneder. RICC originates from the Danish biotech company Santaris Pharma A/S that was acquired by Roche in August 2014. Availability of talent is among the main reasons why the company is investing in Denmark. Roche Diagnostics er markedsleder inden for in vitro-diagnostiske produkter og vvsbaseret cancerdiagnostik. ZURICH Roche Holding AG said Monday it was buying Danish biopharmaceutical firm Santaris Pharma for as much $450 million, as the Swiss giant looks for ways to develop drugs for diseases difficult to address with existing medicines. Discovery and development of miravirsen for the treatment of Hepatitis C. miravirsen is an LNA . They do not need complicated drug delivery vehicles, their manufacturing is scalable and cost-effective, they are well tolerated, and there is potential for oral delivery.[3][7]. . How Should Parents Handle Their Children Being Bullied. Basel, 4 August 2014 Roche to acquire Santaris Pharma to expand discovery and development of RNA-targeting medicines Roche announced today that it has. Roche <ROG.VX> said on Monday it will buy Santaris Pharma, a privately-held Danish biotech company that has developed a new designer molecule, for up to $450 million in cash. Isis's infringement suit against Santaris is based upon Santaris's activities providing antisense drugs and antisense drug discovery services to several pharmaceutical companies. Acquisition to expand Roche's discovery and development of RNA-targeting medicines. PsstTheres a Hidden Market for Six-Figure Jobs. The deep understanding of RNA mechanisms and how to modulate them enables discovery of important novel medicines across multiple therapeutic areas. Santaris Pharma will receive an upfront payment of $10 . The company also worked on collaborations with pharmaceuticals to develop drugs for rare genetic disorders, cancers, cardiovascular disease, and immune and inflammatory diseases. Roche plans to maintain Santaris Pharma's operations . Create a biography. The ruling confirmed that Santaris held exclusive worldwide rights to manufacture, have manufactured, and sell products that comprise LNA as active ingredient for studies performed with a purpose of developing LNA-based drugs for marketing approval. 2004: Began cancer drug development - LNA-based drugs SPC3042 targeting. Layout table for investigator information; Study Director: Clinical Trials: Hoffmann-La Roche: More Information . Acquiring Organization: Roche Roche is a pharmaceutical and diagnostics company that focuses on improving people's lives. Under the terms of the agreement, Santaris Pharma and Roche will collaborate on the discovery of LNA drugs against a multitude of targets across several disease areas. Santaris Pharma is one of the many pharmaceutical company recently acquired by Roche. [3] BioWorld Science Other news to note . 10:33. Santaris Pharma A/S. The company headquarters are located in Basel. This is Roche Holding AG's 12th transaction in the Life Science sector. This website contains information on products which is targeted to a wide range of audiences and could contain product details or information otherwise not accessible or valid in your country. The agreement represents a milestone in the roll-out of LEO Pharmas 2030 strategy which increases the companys focus on new innovative solutions for medical dermatology, it states. These efforts complement other drug discovery efforts within the Roche Group and accelerate the emergence of the new RNA-therapeutic era in human medicine. Instead of integrating Santaris Pharma's research in its activities in Basel, Switzerland, Roche . News; Analysis; Policy & Pricing; Insights; Events; Medtech Acquired. Den schweiziske lgemiddelkoncern har kbt Santaris Pharma for 250. [26], It may require cleanup to comply with Wikipedia's content policies, particularly. Santaris Pharma discovers and develops RNA-targeted therapies to treat infectious diseases and metabolic disorders. Christoph Franz, chairman of Roche, visiting the Roche Innovation Center Copenhagen in 2016. "Roche is the biggest research-based pharmaceutical company in the world, and if we can bring just one or two drugs to . [8] EZN-2968 is an inhibitor of a transcription factor, HIF-1, that is involved in cells ability to undergo angiogenesis and other processes needed for cell survival. 2011: Obtained license from Mass General Hospital for intellectual property related to miR-33 regulations for cardiovascular disorder treatment. It is developing important novel medicines across multiple therapeutic areas. Fremtidsvej 3DK 2970 HrsholmDenmark Open in Google maps. [9], Santaris partnered with several pharmaceuticals companies that wanted to develop LNA oligonucleotides for mRNA and microRNA targets. In the case of Santaris, Roche acquired a novel technology originated by Danish professors at the University of Southern Denmark. Eight years after Santaris Pharma became the Roche Innovation Center Copenhagen, the Swiss owner has decided to up stakes and move activities closer to home in Basel, Switzerland, hoping employees will follow along. Santaris Pharma will receive an upfront payment of $10 million in cash, up to $138 million in potential pre-clinical, clinical, regulatory and sales milestones per product, and funding of ongoing discovery and research activities. PDF. The plan is to expand discovery and development of RNA-targeting medicines. [4] As a result, the Copenhagen site was renamed the Roche Innovation Center Copenhagen (RICC). Founded in 2003, Santaris Pharma is headquartered in Denmark. [10] SPC-4955 inhibits the protein that is necessary for the formation of plasma LDL cholesterol particles. Santaris Pharma has pioneered its proprietary Locked Nucleic Acid (LNA) platform that has contributed to an emerging era of RNA-targeting therapeutics, according to Roche which states that this new class of medicines has the potential to address difficult to treat diseases in a range of therapeutic areas. Acquired by Roche Hrsholm, Hovedstaden, Denmark 10001+ Venture - Series Unknown Private www.santaris.com 194,366 Highlights Acquisitions 1 Total Funding Amount $90.2M Employee Profiles 2 Investors 9 Recent News & Activity Recognizing the broad application of RNA medicines, RICC is collaborating with selected pharmaceutical companies to discover and develop novel Nucleic Acid-Based Medicines within their therapeutic focus areas. Investigators. The acquisition combines Santaris Pharmas next-generation antisense technology and LNA expertise with Roches deep experience in disease biology, chemistry, drug safety, drug formulation, delivery, and development.. Santaris was then founded in 2003 through the merger of two smaller biotech companies. Santaris Pharma has. 2013: Santaris Pharma A/S and Bristol-Myers Squibb form an alliance to develop lead candidates against a limited number of targets, 2013: Santaris Pharma A/S and RaNa form an alliance to develop lead candidates against <10 of RaNAs proprietary RNA targets for the treatment of human diseases. Santaris Pharma has pioneered its proprietary Locked Nucleic Acid (LNA) platform that has contributed to an emerging era of RNA-targeting therapeutics. August 5, 2014 7:55 am Roche Holding AG made an official statement, revealing that it is to acquire the privately held Danish biopharmaceutical company Santaris Pharma in a deal valued at up to 450 million dollars. Roche to acquire Santaris Pharma to expand discovery and development of RNA-targeting medicines. [4] LNA oligonucleotides are shorter than other antisense drugs, which allows them a higher target affinity and potency than regular RNA oligonucleotides. Santaris Pharma maj 2011 - aug. 2014 3 r 4 mneder. You will be notified in advance of any changes in rate or terms. Already a member? Roche announced that it has agreed to acquire Santaris Pharma, a privately held biopharmaceutical company based near Copenhagen, Denmark. In a bid to expand the discovery and development of RNA-targeting medicines, Roche ( RHHBY ) announced that it has entered into an agreement to. Integrating Santaris into Roche IT aug. 2014 - aug. 2015. 2009: Establishment of branch in San Diego, California, United States of America. F. Hoffmann-La Roche AG, commonly known as Roche, is a Swiss multinational healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Santaris Pharma A/S (acquired by Roche) jan. 2014 - sep. 2014 9 mneder. About Roche Headquartered in Basel, Switzerland, Roche is a leader in research-focused healthcare with combined strengths in pharmaceuticals and diagnostics. Its holding company, Roche Holding AG, has shares listed on the SIX Swiss Exchange. Roche to Acquire Santaris Pharma to Expand RNA . The plan is to expand discovery and development of RNA-targeting medicines. Roche will be responsible for the subsequent development and commercialization of products arising from the alliance. Informacin sobre tu dispositivo y conexin a Internet, como tu direccin IP, Actividad de navegacin y bsqueda al utilizar sitios web y aplicaciones de Yahoo. Roche Innovation Center Copenhagen is the home of RNA Molecule Research, an integrated part of Roche Pharma Research and Early Development. LNA drugs are novel therapeutic agents because of their resistance to endonuclease activity. This is Roche Holding AG's 15th largest (disclosed) transaction. Exiqon brought Santaris to court to obtain more rights of LNA technology in 2010. Roche has just announced a $450m deal to acquire Danish company Santaris Pharma, a specialist in a form of antisense therapy that switches off a gene by interacting with messenger RNA (mRNA) to . Roche will make an upfront cash payment of USD 250 million to Santaris Pharma shareholders and make additional contingent payments of up to USD 200 . Under the terms of the agreement, Roche will make an upfront cash payment of USD 250 million to Santaris Pharma shareholders and make additional contingent payments of up to With this acquisition, Aqilion is taking over all rights to the program, now under the name Regulus, from LEO Pharma. J. Donald deBethizy, President and CEO of Santaris Pharma, commented:Roche and Santaris Pharma have complementary capabilities that will help us realize breakthrough medicines. Roche plans to maintain Santaris Pharma's operations in Denmark, where the existing site will be renamed Roche Innovation Center Copenhagen. Nosotros, Yahoo, somos parte de la familia de marcas de Yahoo. 2014. Roche Group Pharmaceuticals pipeline. Rocheplan is to maintain Santaris Pharmas operations in Denmarkwhere the existing site will be renamed Roche Innovation Center Copenhagen. This bridge forms a bi-cyclic structure that locks the ribose conformation and is integral to the high stability and affinity of the LNA to its complementary RNA sequence. 2007: Commencement of preclinical development of SPC3649, a microRNA-targeted drug for the treatment of. Roche is paying $250 million up front to acquire Santaris Pharma, a Danish biotech firm focused on RNA-based therapeutics.Santaris shareholders could reap another $200 million if certain . Santaris Pharma A/S was a biopharmaceutical company founded in 2003 in Copenhagen, Denmark. "Santaris Pharma A/S is a clinical stage biopharmaceutical company developing next generation RNA-silencing drugs for the treatment of cancer and metabolic diseases. Santaris Pharma has pioneered Locked Nucleic Acid (LNA) technology, which has contributed to an emerging era of RNA-targeting therapeutics. Santaris developed a microRNA targeting drug for hepatitis C, miravirsen (SPC3649),[3] which entered Phase II clinical trials in 2010. Santaris Pharma has pioneered its proprietary Locked Nucleic. The acquisition is expected to close in August 2014. These have outlined the results of experiments using LNA oligonucleotides to down-regulate the expression of endogenous microRNAs in primates. [5] RICC houses Roche's RNA Molecule Research, which is part of Roche Pharma Research and Early Development. Swiss pharmaceutical giant Roche Holding AG (RHHBY, ROG.SW, RO.SW) said Monday that it has agreed to buy Denmark-based biopharmaceutical company Santaris Pharma for up to $450 million. Roche, who has a three-digit billion annual turnover, acquired the Danish company, Santaris Pharma, in August 2014 and chose to keep the employees based in Copenhagen. 2014: Santaris Pharma A/S was acquired by Roche and renamed the Roche Innovation Center Copenhagen. Santaris had the worldwide intellectual property rights to the therapeutic applications of locked nucleic acid (LNA) technology. Roche will make an upfront cash payment of USD 250 million to Santaris Pharma shareholders and make additional contingent payments of up toUSD 200 million based on the achievement of certain predetermined milestones. You may cancel your subscription at anytime by calling Please help update this to reflect recent events or newly available information. The project is ready for clinical trials and Aqilion plans to begin clinical development in, Bavarian Nordic has secured a loan facility of EUR 50 million from the European Investment Bank (EIB). J. Donald deBethizy - President & Chief Executive Officer, Henrik Stage, MS. - Chief Financial Officer & EVP Corporate Development, Henrik rum, MSc PhD - VP & Chief Scientific Officer, Michael R. Hodges, MD - VP & Chief Medical Officer, Troels Koch, PhD - VP & Chief Technology Officer, Bo Rode Hansen, PhD - VP, Alliance Management & Partnered Drug Discovery, Santaris Pharama A/S vs. Isis Pharmaceuticals, This page was last edited on 13 April 2022, at 01:08. Santaris employees have co-authored articles published in Nature (2008) [15] and Science (2009). The Roche Innovation Center in Copenhagen, originating from the acquisition of Santaris Pharma in 2014, is a leader in the rapidly emerging field of RNA-targeted drugs. The loan facility has been issued to support the research and development of vaccines against Ebola and other infectious diseases as well as cancer immunotherapies, according to BioSpace.com. Founded in 2003, Santaris Pharma is headquartered in Denmark. Santaris Pharma Santaris Pharma is a biopharmaceutical company focused on the discovery and development of RNA-targeted therapies. The company, which was created in May 2003 through the merger of Cureon A/S and Pantheco A/S, owns the exclusive worldwide rights to the use of locked-nucleic acids (LNA . "The acquisition combines Santaris Pharma's next-generation antisense technology and LNA expertise with Roche's deep experience in disease biology, chemistry . Other areas include viral infections, metabolic, central nervous system disorders and inflammatory diseases. 06-Aug-2014 - F. Hoffmann-La Roche AG Roche to acquire Santaris Pharma Roche announced that it has agreed to acquire Santaris Pharma. Limited time double deal: Free upgrade + up to 35% Off Avis coupon code, Get 15% off AE promo code with text alerts, Sign up for email and receive 20% off at Ballard Designs, Flash sale - 40% off Kitchen appliances, furniture & dinnerware. PDF. "Forbion recognized that Santaris' LNA chemistries were the best in class antisense technology when the firm led the recapitalization of the Company in 2006," said Martien van Osch, Managing . Roche's return to the field of RNAi research looks to be complete, following its $450m deal to acquire Denmark's Santaris Pharma. Roche will make an upfront cash payment of $250 million to shareholders of Santaris Pharma along with milestone payments of $200 million. Rna-Targeting therapeutics efforts complement other drug discovery services to several pharmaceutical companies ).! 2014 - aug. 2015 and Bioinformatics ( 2008 ) [ 15 ] and Science ( 2009 ) oligonucleotides mRNA Care er en af de strste leverandrer af blodsukkermleudstyr til diabeteskontrol oligonucleotide to the target creates a stretch dsRNA! Kindstugatan 1, 111 31 Stockholm largest ( disclosed ) transaction Copenhagen in. That wanted to develop LNA oligonucleotides to down-regulate the expression of endogenous in! 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